METHODS FOR REDUCING CELLULAR SENESCENCE MEDIATED BY DNA DAMAGING AGENTS

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United States of America Patent

APP PUB NO 20150190484A1
SERIAL NO

14661686

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for reducing cellular senescence in a subject, in particular a subject exposed to or at risk of being exposed to a DNA damaging agents, e.g., radiation, by inhibiting PAI-1 activity in the subject with a truncated PAI-1 agent, rPAI-123.

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Patent Owner(s)

Patent OwnerAddress
TRUSTEES OF DARTMOUTH COLLEGE11 ROPE FERRY ROAD ROOM 6210 HANOVER NH 03755

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chung, Eunjoo S Rockville, US 1 0
Citrin, Deborah Eva Bethesda, US 1 0
Mitchell, James Damascus, US 128 3522
Mulligan-Kehoe, Mary Jo Enfield, US 9 175

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