PREDICTING BLADDER CANCER RESPONSIVENESS TO BCG

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United States of America Patent

APP PUB NO 20150185224A1
SERIAL NO

14420837

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Bacillus Calmette-Guerin (BCG) administration plays a central role in managing carcinoma in situ of the bladder. Unfortunately, recurrence or progression of disease is seen in up to 30% of treated patients. Disclosed herein is a method for predicting responsiveness to treatment with BCG based on BCG internalization by bladder cancer cells, the presence or absence of mutations associated with BCG uptake or a combination thereof.

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Patent Owner(s)

Patent OwnerAddress
MEMORIAL SLOAN-KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK NY 10065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barkan, Daniel Tel Aviv, IL 2 2
Bochner, Bernard H Scarsdale, US 1 0
Glickman, Michael Pelham, US 5 30
Iyer, Gopa New York, US 1 0
Jiang, Xuejun Cresskill, US 9 12
Redelman-Sidi, Gil New York, US 1 0
Solit, David New York, US 3 15

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