Methods for detecting an analyte

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United States of America Patent

PATENT NO 10753927
APP PUB NO 20140099731A1
SERIAL NO

13645002

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Abstract

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A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.

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Patent Owner(s)

Patent OwnerAddress
ALERE TECHNOLOGIES GMBH07749 JENA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ermantraut, Eugen Jena, DE 58 518
Kaiser, Thomas Hohlstedt, DE 94 1110
Mobius, Klaus-Peter Zollnitz, DE 4 30
Schulz, Torsten Jena, DE 96 2034
Tuchscheerer, Jens Jena, DE 13 159
Uhlig, Thomas Jena, DE 17 115
Von, Schenk Zu Schweinsberg Alexander Jena, DE 4 59

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