BENZENESULFONAMIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR

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United States of America Patent

SERIAL NO

14553923

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Abstract

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The invention relates to compounds of the formula R1 is selected from the group consisting of hydrogen, linear C1-C3 alkyl and fluorinated linear C1-C3 alkyl; R2 is hydrogen or methyl; R3 is selected from the group consisting of hydrogen, halogen, C1-C2-alkyl, fluorinated C1-C2-alkyl, C1-C2-alkoxy and fluorinated C1-C2-alkoxy, R4 is C1-C2-alkyl or fluorinated C1-C2-alkyl; n is 0, 1 or 2, and the physiologically tolerated salts of these compounds and the N-oxides thereof. The invention also relates to a pharmaceutical composition that comprises at least one compound of the formula I and/or at least one physiologically tolerated acid addition salt thereof, and further to a method for treating disorders that respond beneficially to dopamine D3 receptor antagonists or dopamine D3 agonists, said method comprising administering an effective amount of at least one compound or physiologically tolerated acid addition salt of the formula I to a subject in need thereof.

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Patent Owner(s)

Patent OwnerAddress
ABBVIE DEUTSCHLAND GMBH & CO KGMAX-PLANCK-RING 2A WIESBADEN 65205

International Classification(s)

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  • 2014 Application Filing Year
  • C07D Class
  • 5203 Applications Filed
  • 4627 Patents Issued To-Date
  • 88.93 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bespalov, Anton WIESBADEN, DE 18 63
Braje, Wilfried WIESBADEN, DE 95 431
Drescher, Karla WIESBADEN, DE 77 265
Haupt, Andreas WIESBADEN, DE 99 682
Jongen-Relo, Ana Lucia WIESBADEN, DE 6 2
Lange, Udo WIESBADEN, DE 65 758
Turner, Sean Colm WIESBADEN, DE 31 107
Unger, Liliane WIESBADEN, DE 152 870

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges12662125286874713251301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 80100 +010020030040050060070080090010001100120013001400150016001700180019002000210022002300

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