DUAL MECHANISM INHIBITORS FOR THE TREATMENT OF DISEASE
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United States of America Patent
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app pub date -
Mar 9, 2015
filing date -
May 1, 2009
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Abstract
Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (MAT) act to improve the disease state or condition. Further provided are compositions comprising the compounds. Further provided are methods for treating diseases or conditions, the methods comprising administering compounds according to the invention. One such disease may be glaucoma for which, among other beneficial effects, a marked reduction in intraocular pressure (IOP) may be achieved.
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