COMPOUNDS HAVING MAGNETIC FUNCTIONALITY, IMPLANTS OR GELS DERIVED FROM SAME, AND USE OF BOTH IN ORDER TO DETERMINE THE ENZYME ACTIVITY OF AN ENZYME
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United States of America Patent
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Issued Date -
Jun 25, 2015
app pub date -
Jun 21, 2013
filing date -
Jun 21, 2012
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Abstract
The invention relates to an implant or gel including at least one compound having magnetic functionality, which in turn includes a substrate of at least one enzyme involved in regenerating the extracellular matrix and a plurality of magnetic particles. The invention also relates to a compound having magnetic functionality which includes a substrate of at least one enzyme involved in regenerating the extracellular matrix and a plurality of magnetic particles, preferably with no coating or surface modification, or functionalised with carboxyl groups, for the production of an implant or gel for monitoring an enzyme activity involved in regenerating the extracellular matrix. The substrate is preferably selected from the group that comprises collagen, chondroitin sulphate and hyaluronic acid, and the magnetic particles are superparamagnetic particles.
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