METHODS FOR IDENTIFYING AND INHIBITING GROWTH OF CHEMOTHERAPEUTIC-RESISTANT CANCERS

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United States of America Patent

SERIAL NO

14640403

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Abstract

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The present invention is a biomarker of chemotherapeutic drug-resistant cancer stem cells and a method of inhibiting the growth of drug-resistant cancer stem cells. In one embodiment the cancer stem cells are testicular cancer germ cells. In another embodiment the present invention is a method of overcoming drug resistance in cancer treatment where the combination of low dose decitabine and administration of a chemotherapeutic drug to which cancer cells were resistant results in successful cancer treatment.

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Patent Owner(s)

Patent OwnerAddress
TRUSTEES OF DARTMOUTH COLLEGE11 ROPE FERRY RD ROOM 6210 HANOVER NH 03755

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beyrouthy, Maroun J Lebanon, US 4 2
Spinella, Michael Hanover, US 4 2

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