STRING GRAPH ASSEMBLY FOR POLYPLOID GENOMES
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United States of America Patent
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Jun 18, 2015
app pub date -
Dec 18, 2014
filing date -
Dec 18, 2013
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Abstract
Exemplary embodiments provide methods and systems for string graph assembly of polyploid genomes. Aspects of the exemplary embodiment include receiving a string graph generated from sequence reads of at least 0.5 kb in length; identifying unitigs in the string graph and generating a unitig graph; identifying string bundles in the unitig graph; determining a primary contig from each of the string bundles; and determining associated contigs that contain structural variations compared to the primary contig.
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