COMPOSITION FOR THERMOSTABILIZATION OF HUMAN SERUM ALBUMIN AND METHOD OF PREPARING THERMALLY STABILIZED HUMAN SERUM ALBUMIN USING THE SAME
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Jun 18, 2015
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Dec 18, 2013
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Dec 18, 2012
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Abstract
The present invention relates to a composition for thermostabilization in the preparation of a human serum albumin formulation, comprising a fatty acid selected from the group consisting of C16 to C22 fatty acids or a pharmaceutically acceptable salt thereof; a method of preparing thermally stabilized human serum albumin, comprising: 1) adjusting a concentration of human serum albumin to 1 to 40 mg/mL; and 2) adding the fatty acid or pharmaceutically acceptable salt thereof to the human serum albumin; and a method of preparing a human serum albumin formulation, comprising adding the fatty acid or pharmaceutically acceptable salt thereof to human serum albumin and thermally treating the resultant.
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