COMPOSITIONS AND METHODS FOR TREATING DISEASE
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United States of America Patent
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Issued Date -
Jun 18, 2015
app pub date -
Nov 17, 2014
filing date -
Nov 17, 2013
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Abandoned
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Abstract
Methods are provided for treating fibrotic diseases and conditions or cancer and other dysproliferative diseases by administering to a subject in need there of a therapeutically effective amount of a synergistic composition comprising a phosphatidylinositol 3-kinase inhibitor and a retinoid, optionally including a CYP26 inhibitor, wherein the therapeutically effective amount suppresses fibrosis or the growth of dysproliferative cells in vivo. Compositions comprising a combination of a phosphatidylinositol 3-kinase inhibitor and a retinoid, optionally in combination with a CYP26 inhibitor, are also described.
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