METABOLITES OF THE JANUS KINASE INHIBITOR (R)-3-(4-(7H-PYRROLO[2,3-d]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYLPROPANENITRILE

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United States of America Patent

SERIAL NO

14518419

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Abstract

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The present invention provides active metablites of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.

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Patent Owner(s)

Patent OwnerAddress
INCYTE HOLDINGS CORPORATION1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803
INCYTE CORPORATION1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arvanitis, Argyrios G Kennett Square, US 32 3014
Rodgers, James D Landenberg, US 106 8792
Shepard, Stacey Wilmington, US 76 5089
Shi, Jack Guoen Wilmington, US 7 455

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