BISPECIFIC ANTI-CXCR7 IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

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United States of America Patent

SERIAL NO

14008011

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to particular polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the present invention provides immunoglobulin single variable domains inhibiting CXCR7 mediated tumour growth.

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Patent Owner(s)

  • ABLYNX N.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Descamps, Francis Roeselare, BE 12 105
Gonzalez, Pajuelo Maria Porto, PT 6 25
Leurs, Regorius Amsterdam, NL 12 98
Maussang-Detaille, David André Baptiste Rotterdam, NL 1 6
Merchiers, Pascal Gerard Tielen, BE 14 87
Smit, Martine Amsterdam, NL 9 97
Stortelers, Catelijne Gent, BE 35 236
Van, Rompaey Philippe Melle, BE 11 73
Van, Roy Maarten Zwijnaarde, BE 10 131
Vanlandschoot, Peter Bellem, BE 28 303

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