COBALT PYROPHOSPHATE COMPLEXES AND METHODS OF TREATMENT USING THE COMPLEXES
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United States of America Patent
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Issued Date -
Jun 11, 2015
app pub date -
Feb 17, 2015
filing date -
Oct 21, 2009
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Abandoned
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Abstract
The present invention involves pyrophosphate bridged coordination complexes and the treatment of medical conditions, such as cancer, using the pyrophosphate bridged coordination complexes. The pyrophosphate bridged coordination complexes include four new compounds, [Co(phen)2(H2P2O7)].4H2O(1.4H2O), [Ni(phen)2(H2P2O7)].8H2O(2.8H2O), [Cu(phen)(H2O)(H2P2O7)], and {[Cu(phen)(H2O)(P2O7)][Na2(H2O)8]}.6H2O(4.14H2O) found effective for treating cancer cells. The pyrophosphate bridged coordination complexes also include three compounds, {[Ni(phen)2]2(μ-P2O7)}.27H2O (compound 11), {[Cu(phen)(H2O)]2(μ-P2O7)}.8H2O (compound 12), and {[Co(phen)2]2(μ-25P2O7)}.6MeOH (compound 13), (where phen is 1,10-phenanthroline), whose effectiveness in treating cancer cells was previously unknown.
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