ADENOVIRAL VECTOR-BASED MALARIA VACCINE
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United States of America Patent
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Issued Date -
Jun 11, 2015
app pub date -
Feb 1, 2013
filing date -
Feb 2, 2012
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Abstract
The invention provides an adenovirus or adenoviral vector characterized by comprising a nucleic acid sequence encoding one or more Plasmodium antigens and one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein, as well as a method of inducing an immune response against Plasmodium falciparum in a mammal by administering the adenovirus or adenoviral vector to the mammal.
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