Low-Molecular-Weight Biotechnological Chondroitin 6-Sulphate for Prevention of Osteoarthritis

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United States of America Patent

APP PUB NO 20150152198A1
SERIAL NO

14402646

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Disclosed is a low-molecular-weight (1000-5000 daltons) chondroitin sulphate (CS) produced by chemical sulphation and subsequent depolymerisation of a non-sulphated chondroitin backbone obtained with biotechnology techniques. The CS described is substantially monosulphated, mainly at the 6-position, with very little sulphation at the 4-position, and with a mono/disulphated disaccharide ratio and charge density similar to those of natural CS. Said biotechnological chondroitin 6-sulphate (C6S) is useful in the treatment and prevention of osteoarthritis and in acute and chronic inflammatory processes.

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GNOSIS S P A20121 MILANO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agostinetto, Marco Desio, IT 2 1
Bazza, Paola Desio, IT 9 4
Bianchi, Davide Desio, IT 17 31
Busiello, Immacolata Desio, IT 6 4
Miraglia, Niccolo Desio, IT 8 15
Trentin, Antonella Desio, IT 4 15
Trilli, Antonio Desio, IT 5 4
Valetti, Marco Desio, IT 9 11
Valoti, Ermanno Dalmine, IT 16 27

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