VACCINE COMPOSITION FOR PREVENTING STAPHYLLOCOCCUS AUREUS INFECTION
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United States of America Patent
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May 28, 2015
app pub date -
May 7, 2013
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May 7, 2012
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Abstract
The present invention relates to a vaccine composition for preventing staphylococcus aureus infection containing, as an active ingredient, a ribitol-phosphate which has been modified only by a β-configuration in N-Acetylglucosamine (GlcNAc), a repeating unit of the ribitol-phosphate, or a wall teichoic acid (WTA) containing the repeating unit. The composition according to the present invention contains a coupling motif (an epitope) for an anti-WTA antibody, and thus can be effectively used as a vaccine composition or to prevent staphylococcus aureus infection by generating anti-WTA antibody.
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