PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF BRAIN TUMOR OR TEMODAL RESISTANT GLIOBLASTOMA MULTIFORM COMPRISING AZATHIOPRINE AS AN ACTIVE INGREDIENT

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United States of America Patent

SERIAL NO

14594448

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Abstract

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The present invention relates to a pharmaceutical composition for the prevention or treatment of cancer or Temodal resistant glioblastoma multiform comprising azathioprine as an active ingredient. The azathioprine of the present invention is not only effective in inhibiting the growth of glioblastoma multiform, a kind of brain tumor, but also excellent in treating glioblastoma multiform that displays resistance against Temodal (temozolomide), the conventional therapeutic agent for glioblastoma multiform, so that it can be effectively used as an active ingredient of a pharmaceutical composition for the prevention or treatment of such cancer as brain tumor (particularly, glioblastoma multiform) and particularly Temodal resistant glioblastoma multiform.

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Patent Owner(s)

Patent OwnerAddress
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY141 GAJEONG-RO YUSEONG-GU DAEJEON 34114
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION48 ITAEWON-RO 55-GIL YONGSAN-GU SEOUL 04348

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHO, Heeyeong Daejeon, KR 10 7
CHOI, Gildon Daejeon, KR 15 5
JEONG, Dae Young Daejeon, KR 8 23
KIM, Hyeon Young Chungcheongbuk-do, KR 3 2
LEE, Sunkyung Daejeon, KR 3 2
NAM, Do Hyun Seoul, KR 36 80
PARK, Woo Kyu Chungcheongbuk-do, KR 7 37
SEOL, Ho Jun Busan, KR 3 0

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