IMMUNOMODULATORY METHODS USING NOTCH AGONISTS
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United States of America Patent
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Issued Date -
May 21, 2015
app pub date -
May 7, 2013
filing date -
May 10, 2012
priority date (Note) -
Abandoned
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Abstract
The invention relates to materials and methods for regulating immune pathways using NOTCH and NOTCH agonists. In particular, said agonists may be used in methods for sensitizing CD4+ CD25− cells to CD4+ CD25+ cell-mediated immunosuppression, for enhancing the TGF-β response of CD4+ CD25− cells.
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