TUMOR-INITIATING CELLS AND METHODS OF USE
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United States of America Patent
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app pub date -
Jan 31, 2014
filing date -
Jun 30, 2008
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Abstract
Provided herein are an isolated or enriched population of tumor initiating cells derived from normal cells, cells susceptible to neoplasia, or neoplastic cells. Methods of use of the cells for screening for anti-hyperproliferative agents, and use of the cells for animal models of hyperproliferative disorders including metastatic cancer, diagnostic methods, and therapeutic methods are provided.
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