Microfluidic devices for multi-index biochemical detection

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United States of America Patent

PATENT NO 10758903
APP PUB NO 20150132753A1
SERIAL NO

14398113

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Abstract

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In one aspect, a microfluidic device for multiple reactions is provided, which comprises a reaction channel comprising multiple reaction chambers connected to a closed chamber or an elastic balloon outside of the microfluidic device, wherein a wall of the closed chamber is an elastic membrane; and a control channel comprising an elastic side wall, wherein the intersections between the side wall of the control channel with the reaction channel form multiple pneumatic microvalves. In another aspect, a method for conducting multiple reactions using the microfluidic device is provided, which comprises: a) filling the reaction chambers with a sample; and b) applying pressure to the control channel to expand the elastic side wall of the control channel, wherein the expanded elastic side wall forms a pneumatic microvalve that separates the reaction chambers.

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Patent Owner(s)

Patent OwnerAddress
TSINGHUA UNIVERSITYNO 1 QINGHUAYUAN HAIDIAN DISTRICT BEIJING 100084
CAPITALBIO CORPORATION18 LIFE SCIENCE PARKWAY CHANGPING DISTRICT BEIJING 102206

International Classification(s)

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  • 2013 Application Filing Year
  • F16K Class
  • 1452 Applications Filed
  • 1315 Patents Issued To-Date
  • 90.57 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20132014201520162017201820192020202120220255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Jing Beijing, CN 184 3034
Xing, Wanli Beijing, CN 40 155
Ye, Jiaming Beijing, CN 19 75
Zhang, Kaihuan Beijing, CN 13 7

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  • F16K Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges752445102101 - 1011 - 2021 - 3031 - 40050100150200250300350400450500550600650700750800

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