COMPLEXES OF FULVESTRANT AND ITS DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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United States of America Patent

APP PUB NO 20150132388A1
SERIAL NO

14538184

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to pharmaceutically acceptable complex formulae comprising complexes of Fulvestrant, or a salt, or derivatives thereof and complexation agents and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present invention have improved physicochemical properties which makes the compound orally available and makes oral administration of the compound possible in the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy.

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Patent Owner(s)

Patent OwnerAddress
DRUGGABILITY TECHNOLOGIES IP HOLDCO LIMITEDSWATAR BKR 4013

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ötvös, Zsolt Csongrad, HU 21 55
Angi, Erzsébet Réka Nagykovacsi, HU 12 19
Filipcsei, Genovéva Budapest, HU 28 46
Glavinas, Hristos Szeged, HU 27 36
Kárpáti, Richard Balázs Tatabanya, HU 3 6
Molnár, László Biatorbagy, HU 12 45

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