LOW TEMPERATURE DRYING METHODS FOR FORMING DRUG-CONTAINING POLYMERIC COMPOSITIONS
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Jan 14, 2015
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Dec 29, 2005
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Abstract
The present invention relates to a process for reducing solvent contents in drug-containing polymeric compositions. Specifically, the solvent contents in the drug-containing polymeric compositions are first reduced by one or more conventional drying methods, to a range from about 0.5 wt % to about 10 wt % of the total weight of the polymeric composition. Subsequently, the drug-containing polymeric compositions are further treated by one or more low temperature (i.e., having processing temperatures of less than 60° C.) drying methods for further reduction of the solvent content to less than 10,000 ppm.
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