COMPOSITIONS AND METHODS FOR DIMINISHING AN IMMUNE RESPONSE

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United States of America Patent

SERIAL NO

14407627

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is based upon the discovery that T regulatory type 1 (Tr1) cells express particular cell surface markers that allow for their selection, enrichment, isolation, purification and administration. The ability to use the particular markers described herein to select, enrich, isolate, purity and administer Tr1 cells allows for improved methods of Tr1 therapies for treating a wide variety of diseases and disorders.

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Patent Owner(s)

Patent OwnerAddress
YALE UNIVERSITYTWO WHITNEY AVENUE NEW HAVEN CT 06510
FONDAZIONE TELETHONVIA VARESE 16B ROME 00185
OSPEDALE SAN RAFFAELE SRLVIA OLGETTINA 60 MILANO 20132

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Flavell, Richard A Guilford, US 33 302
Gagliani, Nicola New Haven, US 3 3
Gregori, Silvia Buccinasco (MI), IT 4 3
Huber, Samuel Hamburg, DE 13 155
Magnani, Chiara Francesca Milano (MI), IT 5 15
Roncarolo, Maria Grazia Segrate (MI), IT 23 93

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