System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
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United States of America Patent
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Dec 26, 2017
Grant Date -
May 7, 2015
app pub date -
Jan 7, 2015
filing date -
Feb 12, 2009
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Abstract
Embodiments of the invention provide methods for transdermal delivery of therapeutic agents for treatment of addictive cravings e.g., from nicotine. Embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into skin. A dose of agent is delivered from the assembly into skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel agent out of the assembly. During a second period, a second current having a characteristic to attract agent is used to retain agent in the assembly such that delivery of agent into skin is minimized. In particular embodiments, a dose of agent may be delivered on-demand using an input from the patient using an inhalation sensing device which mimics an inhaled form of tobacco.
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