SYSTEM AND METHOD FOR ALIGNING GENOME SEQUENCE IN CONSIDERATION OF ACCURACY
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United States of America Patent
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Issued Date -
Apr 30, 2015
app pub date -
Oct 31, 2014
filing date -
Oct 31, 2013
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Abstract
There are provided a sequence aligning device in consideration of accuracy, and a method thereof. The sequence aligning apparatus of an embodiment of the present disclosure includes a seed extracting unit configured to extract at least one seed that is exactly matched to a reference sequence from a read; a mapping score calculating unit configured to, with respect to each of the at least one extracted seed, map a left area and a right area of the read to the reference sequence based on the seed at each mapping position of the reference sequence of each seed, and calculate a left mapping score and a right mapping score of each mapping position from the mapping result; and a read aligning unit configured to determine a mapping position in each reference sequence of the at least one seed using the calculated left mapping score and right mapping score.
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