Method For Detecting And Purifying Pancreatic Beta Cells
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United States of America Patent
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N/A
Issued Date -
N/A
app pub date -
Dec 22, 2014
filing date -
Nov 7, 2008
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The invention is based, in part, on the discovery that a polypeptide, referred to herein as Betacam, is selectively expressed on the surface of pancreatic islet cells. Thus, in one aspect, the invention is directed to compositions comprising Betacam or that can be used to detect Betacam. In another aspect, the invention provides methods of detecting (e.g., non-invasively) pancreatic beta cells from a mammalian cell source. Another aspect of the invention is directed to cellular purification of pancreatic beta cells from a heterogeneous cell source of multiple kinds. In another aspect, the invention provides methods of identifying agents that modulate activity of Betacam. In yet another aspect, the invention provides for improved treatment and diagnosis of diabetes.
First Claim
Other Claims data not available