(R)-(-)-1,2-propanediol compositions and methods

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United States of America Patent

APP PUB NO 20150105349A1
SERIAL NO

13987657

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Abstract

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Short-chain 2- to 3-carbon alcohols are used as solvents for cooling agents in the preparation of topical therapeutic and cosmetic formulations. Some of these alcohols, especially ethanol, inhibit the ability of the cooling agent to activate its target receptor. In one embodiment of this invention, (R)-1,2-propanediol is used as an alcoholic solvent for the topical delivery of cooling agents to biological surfaces. This (R)-1,2-propanediol enantiomer has a minimum inhibitory effect on cooling with respect to standard 2- to 3-carbon alcoholic solvents, and functions to substantially protect the agents cooling activity from inhibition when in the presence of a short-chain alcohol such as ethanol.

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Patent Owner(s)

Patent OwnerAddress
WEI EDWARD TBERKELEY CA 94708

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Inventor Name Address # of filed Patents Total Citations
Wei, Edward T Berkeley, US 46 329

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