IN VITRO METHOD FOR PREDICTING DISEASE OUTCOME IN STAGE II COLORECTAL CANCER

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United States of America Patent

APP PUB NO 20150105342A1
SERIAL NO

14397764

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Abstract

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The present invention relates to a method for determining the likelihood of disease outcome of a patient diagnosed with microsatellite stable, stage II colorectal cancer. More in particular, the present invention relates to a method for determining the prognosis of a patient diagnosed with microsatellite stable, stage II colorectal cancer wherein the CpG island methylation status of the promoter of the CHFR gene is determined and wherein methylation of the promoter is indicative of a poor prognosis.

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THE JOHNS HOPKINS UNIVERSITY3400 N CHARLES STREET BALTIMORE MD 21218-2695

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
de, Bruïne Adriaan Pieter Geulle, NL 1 0
Herman, James Bltimore, US 8 157
van, Engeland Manon Maastricht, NL 10 125

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