METHODS OR RISK ASSESSMENT OF PML AND RELATED APPARATUS
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United States of America Patent
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Apr 16, 2015
app pub date -
Oct 16, 2012
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Oct 17, 2011
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The invention provides a method of assessing the risk of occurrence of progressive multifocal leukoencephalopathy (PML) in a subject as well as a method of stratifying a subject undergoing VLA-4 blocking agent treatment for suspension of VLA-4 blocking agent treatment. These methods comprise detecting the level of L-selectin (CD62L) and optionally LFA-1 expressing T cells in a sample from the subject.
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