Genome Surgery with Paired, Permeant Endonuclease Construct
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
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N/A
Issued Date -
Apr 16, 2015
app pub date -
Jul 9, 2013
filing date -
Jul 11, 2012
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A chemical tool and its use in genome surgery includes P2E2 constructs of in, order, a cell penetration component, a DNA binding component and a restriction endonuclease. The method for performing genome surgery includes:
- a) providing one or more recombinant of the P2E2 constructs;b) penetrating a cell with the recombinant P2E2 protein construct;c) forming a protein product in the cell by the processes of transcription and translation or by direct introduction of the P2E2 protein construct to the cell;d) attaching the protein product of the P2E2 construct to one or more targeted genomic sequences within the cell; ande) the endonuclease of the P2E2 construct cutting both strands of the genome at target locations.
First Claim
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