Levels and/or Sustainability of DNA-based Gene Expression

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20150104828A1
SERIAL NO

14269699

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Abstract

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The invention encompasses methods for improving the level and/or sustainability of expression for a target nucleic acid in a eukaryotic cell comprising: (a) modifying the target nucleic acid to introduce or to comprise signals that limit or constrain the positions of nucleosome cores, and (b) introducing the modified target nucleic acid into the eukaryotic cell, wherein the modified target nucleic acid has improved levels and/or sustainability of expression compared to original unmodified nucleic acid.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYOFFICE OF THE GENERAL COUNSEL BLDG 170 3RD FL MAIN QUAD PO BOX 20386 STANFORD CA 94305-2038

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fire, Andrew Washington, US 25 2348
Gracey, Lia Stanford, US 2 14
Lui, Weng-Onn Stockholm, SE 2 14

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