CARDIAC MUSCLE REPAIR OR REGENERATION USING BONE MARROW-DERIVED STEM CELLS

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United States of America Patent

SERIAL NO

14493864

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Abstract

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Disclosed are compositions and methods for repairing and/or regenerating cardiac tissue by administering adult bone marrow-derived stem cells to an individual. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.

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Patent Owner(s)

Patent OwnerAddress
MESOBLAST INTERNATIONAL SÀRLROUTE DE PRE-BOIS 20 MEYRIN 1217

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gordon, Stephen L Columbia, US 26 845
Mackay, Alastair Morgan Towson, US 16 608
Pittenger, Mark F Severna Park, US 45 1533

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