PHARMACEUTICAL COMPOSITION, METHOD AND KIT FOR DETECTING HUMAN MELANOMA CELLS
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United States of America Patent
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Apr 9, 2015
app pub date -
Jun 19, 2014
filing date -
Oct 4, 2013
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Abstract
The present disclosure is related to a pharmaceutical composition for detecting human melanoma cells, including: a liposome, a biomolecule having specificity for αvβ3 integrin and a radionuclide. The present disclosure also provides a method using the pharmaceutical composition for detecting human melanoma cells and a kit performing the method. By means of the specificity of the biomolecule for the αvβ3 integrin, the liposome is enabled to have recognition ability and facilitates the interaction between the liposome and a target cell. Therefore, the present disclosure is capable of being widely applied in the field of melanoma diagnosis, lymphatic metastasis detection and post-surgical monitoring, and so on.
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