OPTIMIZE ANALYTE DYNAMIC RANGE IN GAS CHROMATOGRAPHY
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United States of America Patent
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Issued Date -
Apr 9, 2015
app pub date -
Apr 14, 2013
filing date -
May 14, 2012
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Abandoned
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Abstract
A non-specific gas analyzer with a wide dynamic range of concentration is used to assess the gas sample for total load of volatile organic constituents, and then control either a dilution with neutral gas or the quantity of sample aspirated in order to consistently deliver an appropriate total load of volatile analyte to a high-sensitivity analyzer. Such high-sensitivity analyzers may be gas chromatography combined with mass spectrometry or related mass spectrometry configurations, such as selected ion flow tube mass spectrometry, gas chromatography combined with ion mobility spectrometry, or related ion mobility configurations such as differential mobility spectrometry.
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