Bendamustine HCL Stable Lyophilized Formulations
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United States of America Patent
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Issued Date -
Mar 26, 2015
app pub date -
Sep 25, 2014
filing date -
Sep 25, 2013
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Abstract
The present invention provides a lyophilized bendamustine hydrochloride (HCL) pharmaceutical composition. The present invention further provides methods of producing the lyophilized bendamustine HCL composition from a composition including bendamustine HCL, mannitol, formic acid, and water. The pharmaceutical formulation can be used for any disease that is sensitive to treatment with bendamustine, such as neoplastic diseases.
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