STABLE DOSAGE FORMS OF SKELETAL MUSCLE RELAXANTS WITH EXTENDED RELEASE COATING
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United States of America Patent
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Apr 16, 2013
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Apr 17, 2012
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Abstract
A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed along with a method of preparation therefor. The dosage form comprises active core particles which are individually surrounded by a water insoluble polymer coating which lacks plasticizer.
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