1,2,4-Oxadiazole Derivatives as Immunomodulators

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United States of America Patent

SERIAL NO

14478759

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to 1,2,4-oxadiazole and 1,2,4-thiadiazole compounds as therapeutic agents capable of inhibiting the programmed cell death 1 (PD1) signaling pathway. The invention also refers to derivatives of the therapeutic agents. The invention also encompasses the use of the said therapeutic agents and derivatives for treatment of disorders via immunopotentiation comprising inhibition of immunosuppressive signal induced due to PD-1, PD-L1, or PD-L2 and therapies using them.

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Patent Owner(s)

Patent OwnerAddress
AURIGENE ONCOLOGY LIMITEDBANGALORE

International Classification(s)

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  • 2014 Application Filing Year
  • A61K Class
  • 14144 Applications Filed
  • 11600 Patents Issued To-Date
  • 82.02 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Naremaddepalli, Seetharamaiah Setty Sudarshan Bangalore, IN 28 248
Ramachandra, Muralidhara Bangalore, IN 52 528
Sasikumar, Pottayil Govindan Nair Bangalore, IN 31 276

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Patent Citation Ranking

  • 49 Citation Count
  • A61K Class
  • 99.10 % this patent is cited more than
  • 10 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges4055742610302931335621135761001 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0500100015002000250030003500400045005000550060006500700075008000

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