Treatment of Obesity and Obesity-Related Disorders by Pharmalogical Targeting of Kv 1.3 Potassium Channels

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United States of America Patent

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14347602

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Abstract

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Activation of brown adipose tissue, treatment of obesity and/or treatment of obesity-related disorders in human or non-human animal subjects by administering to the subject a potassium channel inhibiting agent. The potassium channel inhibiting agent may comprise ShK toxin or a modified ShK toxin. Examples of modified ShK toxins include ShK-186.

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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA1111 FRANKLIN STREET 5TH FLOOR OAKLAND CA 94607-5200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chandy, K George Laguna Beach, US 16 59
Eckel-Mahan, Kristin Lynn Irvine, US 2 5
Iadonato, Shawn Seattle, US 3 6
Mirbolooki, M Reza Orange, US 2 5
Mukherjee, Jogesh Irvine, US 2 5
Sassone-Corsi, Paolo Laguna Beach, US 4 8
Upadhayay, Sanjeev Kumar Irvine, US 2 5
Wang, Ping H Newport Coast, US 6 12

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