TRYPTOPHAN AS THE FINGERPRINT FOR DISTINGUISHING AGRESSIVENESS AMONG CANCER CELL LINES USING NATIVE FLUORESCENCE SPECTROSCOPY
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Mar 12, 2015
app pub date -
Sep 12, 2014
filing date -
Sep 12, 2013
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Tryptophan is used as the key native marker in cells to determine the level of aggressiveness of cancer cell lines using the native fluorescence spectroscopy. A ratio R of the fluorescence from tryptophan at 340 nm to that from the NADH at 440-460 nm is demonstrated to be associated with aggressiveness of the cancer cells. The higher the ratio R, the more aggressive the tumor towards metastasis.
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