Tolerisation-Inducing Composition
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United States of America Patent
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Issued Date -
Mar 12, 2015
app pub date -
Apr 2, 2013
filing date -
Apr 2, 2012
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a composition comprising a tolerogenic peptide and a GSK-3 inhibitor and uses thereof. The invention also relates to the use of a GSK-3 inhibitor to accelerate the peptide-mediated shift in secretion profile of lymphocytes from pro-inflammatory to anti-inflammatory cytokines. The GSK-3 inhibitor may be used to enhance antigen-specific immunotherapy.
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