Methods and Kits for Analyzing Biomarkers in a Signal Transduction Pathway

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United States of America Patent

SERIAL NO

14478637

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided are methods and kits for analyzing biomarkers in one or more signal transduction pathways in a cell. In some embodiments, the methods and kits of the invention permit simultaneous analysis of more than one biomarker and/or more than one signal transduction pathway. In some embodiments, the invention provides methods for detecting whether a cell treated with an agent targeting a targeted biomarker is responding to the agent, or whether the cell is developing resistance to the agent. In some embodiments, the invention provides methods for determining which biomarker to target in a diseased or damaged cell, or which pathway an agent is targeting in an agent-treated cell. The invention provides kits for carrying out the described methods.

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Patent Owner(s)

Patent OwnerAddress
PROTERIXBIO INC1 FORTUNE DRIVE BILLERICA MA 01821

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alderman, Edward Marshall Framingham, US 2 1
Beausang, Lee Anne Norfolk, US 9 45
Dickerson, Matthew William Dorchester, US 2 14
Latterich, Martin San Marcos, US 9 151
Masters, Brett Peter Belmont, US 4 17

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