METHODS FOR DETERMINING THE TROPISM AND RECEPTOR USAGE OF A VIRUS, IN PARTICULAR HIV, IN BODY SAMPLES TAKEN FROM THE CIRCULATION
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United States of America Patent
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Issued Date -
Feb 26, 2015
app pub date -
Mar 15, 2013
filing date -
Mar 19, 2012
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Abandoned
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Abstract
The present invention relates to microarrays, sets of primers and methods for determining the co-receptor usage of a virus, in particular whether HIV uses CXCR4 or CCR5 as co-receptor. The methods and compositions of the invention are based on microRNA analysis. The invention can be used to determine virus tropism in any species or organism that expresses microRNAs, particularly in human beings.
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