HUMANIZED MOUSE
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United States of America Patent
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Feb 19, 2015
app pub date -
Mar 27, 2012
filing date -
Mar 27, 2012
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Abstract
The present invention provides embryonic stem cells obtainable from an embryo of an immunodeficient mouse which is deficient in both Rag2 and Jak3 genes by culture in the presence of a GSK3 inhibitor and an MEK inhibitor, as well as a transgenic mouse, which is created with the use of these embryonic stem cells.
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