Drug Delivery Conjugate Capable of Controlled Release, and Use Thereof

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United States of America Patent

APP PUB NO 20150051269A1
SERIAL NO

14384509

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a hydrophobic drug delivery conjugate, to which cyclodextrin, poly(maleic anhydride), and a hydrophobic drug are bonded, and to a pharmaceutical composition comprising the hydrophobic drug delivery conjugate as an active ingredient. The hydrophobic drug delivery conjugate according to the present invention can effectively control the release rate and the delivery rate of a hydrophobic drug by regulating the physicochemical bonding and/or composition of the cyclodextrin, poly(maleic anhydride), and hydrophobic drug, and can also increase the effect of the drug by significantly increasing the solubility of the hydrophobic drug. Further, the present invention can enable the type of the hydrophobic drug to be varied, as well as a peptide having target directivity to be introduced into a surface of the conjugate, such that the present invention can be applied to the treatment of various diseases in addition to cancer treatment.

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Patent Owner(s)

Patent OwnerAddress
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION(KYUNGPOOK NATIONAL UNIVERSITY SANGYEOK-DONG) 80 DAEHAK-RO BUK-GU DAEGU 41566 41566

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hoffman, Allan Daegu, KR 2 18
Kim, In San Daegu, KR 21 33
Kim, Won Jong Gyeongsangbuk-do, KR 78 328
Lee, Byung Heon Daegu, KR 6 11
Namgung, Ran Gyeonggi-do, KR 31 74

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