MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION

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United States of America Patent

APP PUB NO 20150050708A1
SERIAL NO

14213806

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Abstract

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Provided herein are non-naturally occurring microbial organisms having a formaldehyde fixation pathway and a formate assimilation pathway, which can further include a methanol metabolic pathway, a methanol oxidation pathway, a hydrogenase and/or a carbon monoxide dehydrogenase. These microbial organisms can further include a butadiene, 1,3-butanediol, crotyl alcohol or 3-buten-2-ol pathway. Additionally provided are methods of using such microbial organisms to produce butadiene, 1,3-butanediol, crotyl alcohol or 3-buten-2-ol.

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Patent Owner(s)

Patent OwnerAddress
GENOMATICA INC4757 NEXUS CENTER DRIVE SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ANDRAE, Stefan San Diego, US 33 120
BURGARD, Anthony P Bellefonte, US 199 3095
OSTERHOUT, Robin E San Diego, US 156 1473
PHARKYA, Priti San Diego, US 156 1697

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