METHOD FOR IDENTIFYING DISEASE ASSOCIATED WITH ABUNDANCE OF TDP-43 IN CELL
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Feb 12, 2015
app pub date -
Feb 28, 2013
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Feb 28, 2012
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Abstract
The present invention aims to develop and provide a method for identifying a disease associated with the abundance of TDP-43 in cells and a method for producing a TDP-43 binding inhibitor. By measuring the abundance of a measurement substance, the amount of binding between a measurement substance and TDP-43, etc. in cells obtained from a subject, it is identified whether or not the subject is suffering from a disease associated with the abundance of TDP-43 in cells. Also, a drug which can significantly reduce the binding between a measurement substance and TDP-43 is produced by adding a drug candidate substance.
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