METHODS AND COMPOSITIONS FOR TREATING PAIN
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United States of America Patent
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Issued Date -
Feb 5, 2015
app pub date -
Feb 11, 2013
filing date -
Feb 11, 2012
priority date (Note) -
Abandoned
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Abstract
The disclosure provides a new use of adenosine analogs for the treatment of pain through activation of neurokinin 1 (NK1) receptor signaling pathway, thereby inducing the activation of M-type potassium channel to induce outward currents. A method and pharmaceutical composition for treating pain comprising an adenonsine analog that activates NK1 receptor signaling, thereby inducing outward current are also provided.
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