METHOD OF PRODUCING HUMAN RETINAL PIGMENTED EPITHELIAL CELLS
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United States of America Patent
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Issued Date -
Feb 5, 2015
app pub date -
Dec 20, 2011
filing date -
Dec 20, 2010
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Abstract
The production of human retinal pigment epithelial cells having a step of incubating human pluripotent stem cells with binder molecules binding to terminal N-acetyllactosamine (Galβ1-4Glc NAc) and/or blood group H determinant type 2 (Fucα1-2Galβ1-4Glc NAc). A method of using lectin ECA in a culture of human pluripotent stem cells in order to support the stem cells to differentiate into retinal pigment epithelial cells is also disclosed.
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