NEGATIVE MODULATOR OF HEDGEHOG SIGNALLING FOR USE IN TREATING TH2-MEDIATED DISEASES
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United States of America Patent
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Issued Date -
Feb 5, 2015
app pub date -
Mar 15, 2013
filing date -
Mar 16, 2012
priority date (Note) -
Abandoned
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Abstract
The invention provides means for treating Th1- and Th2-mediated diseases, such as asthma, allergic dermatitis and Th2-driven cancer. The invention extends to pharmaceutical compositions for use in treating such conditions, and to methods of treatment. The invention also extends to adjuvants and vaccines per se, and to their use in enhancing the immunomodulatory activity of immunogens.
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