USE OF 5-AMINOLEVULINIC ACID AND DERIVATIVES IN A SOLID FORM FOR PHOTODYNAMIC TREATMENT AND DIAGNOSIS

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United States of America Patent

SERIAL NO

14333979

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Abstract

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The present invention relates to the use of a photosensitiser which is 5-ALA or a precursor or derivative thereof (e.g. an ALA ester), in the manufacture of a pharmaceutical product for use in the photodynamic treatment or diagnosis of cancer, an infection associated with cancer, or in the treatment or diagnosis of a non-cancerous condition, wherein said pharmaceutical product is in the form of a solid. The invention also relates to solid pharmaceutical products for use in such methods, e.g. suppositories, pessaries, tablets, pellets and capsules which comprise 5-ALA or a precursor or derivative thereof (e.g. an ALA ester) and at least one pharmaceutically acceptable carrier or excipient. Such products are particularly suitable for use in the photodynamic treatment or diagnosis of cancerous or non-cancerous conditions in the lower part of the gastrointestinal system or in the female reproductive system, e.g. in the treatment or diagnosis of colorectal cancer or cervical cancer.

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Patent Owner(s)

Patent OwnerAddress
PHOTOCURE ASA0275 OSLO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Braenden, Jon Erik Oslo, NO 10 115
Godal, Aslak Oslo, NO 28 400
Klaveness, Jo Oslo, NO 187 4245
Klem, Bjorn Oslo, NO 6 24
Stensrud, Gry Nittedal, NO 6 35

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